Leonardo Jaimes, MD

All articles by Leonardo Jaimes, MD

• New data on Deramiocel shows significant cardiac benefits in DMD

  Dermamiocel appears to effectively prevent cardiac scarring (fibrosis) in patients with Duchenne muscular dystrophy (DMD).

• Study examines effect of sleep problems in early DMD

  Early-stage DMD sleep problems are primarily behavioral and not yet physiologically impactful, according to a recently published study.

• Study highlights impact of body fat, blood pressure on heart health in DMD

  Modifiable cardiovascular risk factors are associated with adverse changes in the heart muscle of DMD patients.

• Study identifies a critical window for orthopedic surgery in DMD

  Orthopedic surgery in patients with DMD should be performed within the first year after initial gait loss for a higher chance of success.

• Satellos reports promising early results for SAT-3247 in DMD

  SAT-3247, an investigational oral therapy targeting muscle regeneration in DMD, improved grip strength in a small clinical trial.

• Glucocorticoids may delay respiratory decline in DMD

  The use of corticosteroid treatment could delay respiratory failure in patients with Duchenne muscular dystrophy (DMD).

• KER-065 granted FDA Orphan Drug designation for DMD

  KER-065, an experimental Duchenne muscular dystrophy (DMD) drug, has been granted Orphan Drug designation by the FDA.

• Dyne Therapeutics receives Breakthrough Therapy designation for DYNE-251

  DYNE-251, developed by Dyne Therapeutics and aimed at treating DMD, has received a Breakthrough Therapy Designation.

• Case report examines acute respiratory distress in a teenage girl with DMD

  A recent case report examines the rare case of a teenage girl with DMD that was complicated by acute respiratory distress syndrome.

• Sarepta voluntarily pauses Elevidys shipments in the US

  Sarepta Therapeutics has announced that it will voluntarily stop all shipments of the DMD therapeutic agent Elevidys.