Ariana Boswell

All articles by Ariana Boswell

• Can adults with DMD live independently?

  For individuals with DMD, “living on your own” can take on many different meanings.

• Regular use of lung volume recruitment therapy low in DMD

  Fewer than half of participants with DMD who were prescribed LVR therapy adhered to their treatment protocol, a study found.

• Trehalose may improve effects of microdystrophin therapy in DMD

  Researchers found that trehalose further improved cellular function in animal models of DMD treated with microdystrophin therapy.

• Synthetic molecule prevents DMD in mouse model

  A study found that a synthetic compound known as a BB polymer may protect skeletal and cardiac muscles from damage in DMD.

• Experimental drug improves gut-muscle crosstalk in DMD mice

  Researchers found that targeting gut microbiome dysfunction in a mouse model of DMD improves muscle health and function.

• How do genetic variants impact DMD treatment and prognosis?

  The type of genetic variant a person with DMD has can impact which therapies they are eligible for.

• What genetic changes cause DMD?

  The DMD gene is the largest known gene, making it more prone to mutations.

• What are mdx mice, and why are they used in research?

  Mdx mice have a mutation in the gene that codes for the protein dystrophin, which is mutated in patients with DMD.

• More awareness needed of uncommon severe comorbidities in DMD

  A recent study identified many severe comorbidities in patients with DMD, including gastrointestinal, cardiovascular and kidney conditions.

• Eteplirsen delays cardiac decline in DMD clinical trials

  A recent study found that individuals with DMD who receive eteplirsen have slower declines in cardiac function than those who do not.